产品货号：
Z35617
中文名称：
MUM1/IRF4抗体
英文名称：
Anti-MUM1/IRF4 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-MUM1/IRF4 Antibody |
| 指标别名 | IRF 4;IRF4;LSIRF;Multiple myeloma oncogene 1;MUM1;MUM1/IRF4;NF EM5 |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,ICC/IF,IP,FCM |
| 基因名称 | IRF4 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human MUM1 Melanoma associated antigen (mutated) 1 (MUM1,EXPAND1) is a PWWP-domain containing chromatin binding protein involved in maintaining chromatin architecture of interphase chromosomes. |
| 实际分子量 | 52KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Interferon regulatory factor 4 (IRF4),also known as MUM1,is a protein that in humans is encoded by the IRF4 gene.It is located on 6p25.3.IRF4 is a transcription factor,and it is essential for the development of T helper-2 (Th2) cells,IL17 -producing Th17 cells,and IL9 -producing Th9 cells.In melanocytic cells,the IRF4 gene may be regulated by MITF.IRF4 is a transcription factor that has been implicated in acute leukemia.This gene is strongly associated with pigmentation,sensitivity of skin to sun exposure,freckles,blue eyes,and brown hair color.What's more,IRF4 inhibition is toxic to myeloma cell lines,regardless of transforming oncogenic mechanism. |
| Uniprot ID | Q15306 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:20～100ICC/IF Immunocytochemistry/Immunofluorescence(ICC/IF) 1:20～100 Immunocoprecipitation 1:20 Flow cytometry (FCM) 1:20 |
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